Visual disturbances with clomiphene.
نویسنده
چکیده
Clomiphene is a widely prescribed drug for the treatment of infertility. Visual symptoms that occur as a side effect of this drug are uncommon. Some doctors may neglect to mention this side effect when prescribing clomiphene. Thus these visual disturbances can be very alarming to the patient and may also pose a hazard if the patient is doing activities such as driving or operating machinery. The patient should be told to stop taking clomiphene and ophthalmologic evaluation should be performed. Although visual disturbances generally cease on stopping clomiphene, some women may experience persistent visual disturbances.
منابع مشابه
Association between clomiphene citrate and visual disturbances with special emphasis on central retinal vein occlusion: a review.
OBJECTIVES To determine whether clomiphene citrate (CC) can be implicated as a cause for central retinal vein occlusion (CRVO) and other visual disturbances. METHODS For this systematic review, we performed a search of the following databases: PubMed (1976 to November 2009), Medline Plus 2009, Cochrane Library (1996 to November 2009), Google and Google Scholar (1996 to November 2009). Thirty-...
متن کاملEffects of Metformin on Ovulation and Pregnancy Rate in Women with Clomiphene Resistant Poly Cystic Ovary Syndrome
Background To evaluate the effect of metformin on ovulation and pregnancy rate in clomiphene citrate resistant women with polycystic ovary syndrome (PCOS). MaterialsAndMethods In this clinical trial each patient, regarding her previous resistance to Clomiphene, served as her own control. A total of 35 clomiphene citrate resistant PCOS patients, referring to Royan institute were studied. Clomiph...
متن کاملP-227: The Survey on Endometrial Thickness and Echo Pattern Changes in Consecutive Cycles of Clomiphene Citrate Therapy in Infertile Women
Background: One of the most common causes of infertility in women is ovulatory dysfunction (PCOS) and the choice of treatment is clomiphene citrate. One of the mechanism of dichotomy between the rate of ovulation and pregnancy is anti estrogenic effects of clomiphene citrate on endometrium. According to its long half life, the anti estrogenic effects probably exacerbate in consecutive cycles. W...
متن کاملComparison of the Effects of Letrozole and Clomiphene Citrate on Ovulation and Pregnancy Rate in Patients with Polycystic Ovary Syndrome
Background: For more than four decades clomiphene citrate has been the first line of the treatment for ovulatory disorders. The aim of this study was to compare the effects of letrozole and clomiphene citrate on ovulation and pregnancy rate in patients with polycystic ovary syndrome. Methods: In this prospective double-blind study, 100 patients with polycystic ovary syndrome were randomized int...
متن کاملP-192: Association of Cytochrome P450 2D6 (CYP2D6) Gene Polymorphism with Clomiphene Citrate Treatment in Iranian Infertile Women with Polycystic Ovary Syndrome
Background: Clomiphene Citrate (CC) is the most frequently administered drug for the treatment of female infertility [e.g. polycystic ovary syndrome (PCOS)]; which aims at restoring ovulation. Clomiphene is metabolized by CYP2D6, an important enzyme responsible for the metabolism of approximately 25% of clinically used drugs. CYP2D6 is very polymorphic and thought to result in inter- individual...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Medical journal of Malaysia
دوره 57 2 شماره
صفحات -
تاریخ انتشار 2002